Articles

Dogs + Tumors

  • The most common forms of cutaneous lymphoma are epitheliotropic lymphoma and dermal lymphoma. No specific risk factors or causes have been identified in the development of cutaneous lymphoma. Generally, cutaneous lymphoma can appear as various-sized irritated, ulcerated, or infected patches anywhere on the skin, including the gums, nose, or lip margins. These areas may become ulcerated and bleed, or become crusted. Secondary infections are possible. By far, the most common treatment for cutaneous lymphoma is chemotherapy. Unfortunately, the response to treatment, although initially encouraging, is typically short-lived, with gradual return of the tumors.

  • This is any tumor originating from the mammary gland tissues. In the dog, most tumors of this type are cured by complete surgical removal, but over time a few progress to malignancy and start to spread to other parts of the body (metastasis).

  • This is a tumor originating from the mammary gland tissues that has been classified as malignant (invasive and capable of spreading). Although some of these cancers are cured by surgical removal, others will recur locally and some spread to other parts of the body (metastasis).

  • A mast cell tumor (MCT) is a type of tumor consisting of mast cells. Mast cell tumors most commonly form nodules or masses in the skin, they can also affect other areas of the body, including the spleen, liver, intestine, and bone marrow. MCTs are particularly common in Boxers, Bull Terriers, Boston Terriers, and Labrador Retrievers. This cancer is typically diagnosed via fine needle aspiration. This tumor's behavior is complex and depends on many factors. Despite the range in behavior and prognoses, MCTs are actually one of the most treatable types of cancer. Depending on the grade, surgery, chemotherapy, and/or radiation therapy are treatments for MCTs.

  • Mast cells originate or are formed in the bone marrow but complete their maturation in peripheral tissues. They are found in all tissues of the body but concentrate near surfaces in contact with the external environment such as the skin, respiratory and digestive tracts.

  • Melanocytes are cells that produce a pigment called melanin. A melanoma is an abnormal production of these cells in a dysregulated manner that forms a nodule, mass, or other form of lesion. Melanomas of the skin may develop anywhere on the body and are not typically bothersome. Toe melanomas, however, can be much more painful and concerning for your pet's health. Melanomas are often black in color but some do not produce pigment (amelanotic melanoma). Fine needle aspiration or biopsy may be used for diagnosis. Melanomas of the skin and toes are treated surgically and radiation therapy may be discussed.

  • Squamous cell carcinoma in situ is a disordered growth of the skin epidermis that may extend to include epithelium of the upper part of the hair follicles.

  • The phrase 'multidrug resistance mutation 1 (MDR1)' refers to a specific mutation that can occur at a gene known as the MDR1 gene, also known as the ABCB1 gene. Many herding breeds (most commonly Collies and Australian Shepherds) have a mutation at the MDR1 gene that makes them more sensitive to the negative effects of certain medications.

  • In some cases, chronic inflammation of the nose (rhinitis) leads to proliferation (hyperplasia) and formation of polyps in the nose or throat. These polyps are not cancerous but may need removal.

  • Neuroendocrine cells produce specialized chemical substances called neuroendocrine hormones. These hormones affect the rates of specific chemical reactions in nearby cells or in other tissues throughout the body.